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With rising pressure and an increase in expected academic performance in schools across the United States, students are experiencing higher levels of stress than ever before. To address this issue, the present study examined the impact of mindfulness-based yoga interventions on fifth-grade students' perceived stress and anxiety levels through a mixed methods research approach. Quantitative data were collected from students through a pre- and post-questionnaire while qualitative data were garnered through an interview with the classroom teacher. Findings revealed that following the intervention period, students reported a decrease in stress levels (9.29%) and a slight increase in anxiety levels (1.9%). Particularly, males in the remedial class displayed changes in both a decrease in stress (16.68%) and anxiety (31.58%) levels. Additionally, the following themes emerged from the qualitative data: (a) teacher perceptions of students' anxiety and stress in the classroom; (b) transfer of mindfulness-based yoga skills; and (c) creating a positive transition. These results suggest that mindfulness-based yoga can be a positive tool for the classroom to reduce students' anxiety and stress.